Chromosomal aberrations in human peripheral blood lymphocytes after exposure to ionizing radiation
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چکیده
منابع مشابه
Chromosomal Aberrations in Human Peripheral Blood Lymphocytes after Exposure to Ionizing Radiation
Biological dosimetry using chromosome aberration analyses in human peripheral blood lymphocytes is suitable and useful tool for estimating the dose when a nuclear or radiological emergency is investigated. Blood samples from five healthy donors were obtained to establish dose-response calibration curves for chromosomal aberrations after exposure to ionizing radiation. In this work, dicentric as...
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Blood lymphocytes from xeroderma pigmentosum (XP) and Fanconi anemia (FA) patients were assessed for their sensitivity to ionizing radiation by estimating the frequency of X-ray (1 and 2 Gy)-induced chromosome aberrations (CA). The frequencies of aberrations in the whole genome were estimated in Giemsa-stained preparations of lymphocytes irradiated at G0 or G2 stages. The frequencies of translo...
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Aim: Analysis of the results of cytogenetic examination and reconstruction of irradiation doses by the frequency of chromosome aberrations in the liquidators of the consequences of the Chernobyl NPP accident. Materials and methods: Over 1500 people who worked in the zone of the accident predominantly in 1986 and in 1987 have been examined since 1986. All of them were examined by means of the cl...
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Purpose: The relationship between biological effects and low doses of radiation is still uncertain, especially for high-LET radiation exposures. Estimates of risk from exposure to low doses and low dose rates are often extrapolated from the Japanese atomic bomb survivor data using either linear or linear-quadratic models fitted to dose–response data. In this study, we determined the dose–respon...
متن کاملComparison of chromosome aberrations in peripheral blood lymphocytes from people occupationally exposed to ionizing and radiofrequency radiation.
The genotoxic effects of occupational exposure to ionizing and non-ionizing radiation were investigated in 25 physicians and nurses working in hospitals and in 20 individuals working at radio-relay stations. Examination was conducted by chromosome aberration analysis of peripheral blood lymphocytes. The data showed that total number of chromosome aberrations in people exposed to ionizing and ra...
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ژورنال
عنوان ژورنال: Genome Integrity
سال: 2016
ISSN: 2041-9414
DOI: 10.4103/2041-9414.197172